| Reaction Details |
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 | Report a problem with these data |
| Target | Programmed cell death protein 4 |
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| Ligand | BDBM50000298 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_776474 (CHEMBL1913571) |
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| IC50 | 880±n/a nM |
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| Citation |  Zhao, LX; Huang, SX; Tang, SK; Jiang, CL; Duan, Y; Beutler, JA; Henrich, CJ; McMahon, JB; Schmid, T; Blees, JS; Colburn, NH; Rajski, SR; Shen, B Actinopolysporins A-C and tubercidin as a Pdcd4 stabilizer from the halophilic actinomycete Actinopolyspora erythraea YIM 90600. J Nat Prod74:1990-5 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Programmed cell death protein 4 |
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| Name: | Programmed cell death protein 4 |
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| Synonyms: | H731 | Neoplastic transformation inhibitor protein | Nuclear antigen H731-like | PDCD4 | PDCD4_HUMAN | Protein 197/15a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51720.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_776474 |
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| Residue: | 469 |
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| Sequence: | MDVENEQILNVNPADPDNLSDSLFSGDEENAGTEEIKNEINGNWISASSINEARINAKAK
RRLRKNSSRDSGRGDSVSDSGSDALRSGLTVPTSPKGRLLDRRSRSGKGRGLPKKGGAGG
KGVWGTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLPLDERAFEKTLTPIIQEYFEHGD
TNEVAEMLRDLNLGEMKSGVPVLAVSLALEGKASHREMTSKLLSDLCGTVMSTTDVEKSF
DKLLKDLPELALDTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTVDCVQARAALDKATV
LLSMSKGGKRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPHFH
HELVYEAIIMVLESTGESTFKMILDLLKSLWKSSTITVDQMKRGYERIYNEIPDINLDVP
HSYSVLERFVEECFQAGIISKQLRDLCPSRGRKRFVSEGDGGRLKPESY
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| BDBM50000298 |
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| n/a |
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| Name | BDBM50000298 |
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| Synonyms: | '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL | (2R,3R,4S,5R)-2-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol | 2-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol | 2-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol (Tubercidin) | 2-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol(tubercidin) | CHEMBL267099 | TUBERCIDIN | cid_6245 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H14N4O4 |
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| Mol. Mass. | 266.2533 |
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| SMILES | Nc1ncnc2n(ccc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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