| Reaction Details |
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 | Report a problem with these data |
| Target | Calcitonin gene-related peptide 1 |
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| Ligand | BDBM50356282 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_775007 (CHEMBL1912162) |
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| IC50 | 0.120000±n/a nM |
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| Citation |  Zartman, CB; Bell, IM; Gallicchio, SN; Graham, SL; Kane, SA; Mallee, JJ; Rutledge, RZ; Salvatore, CA; Vacca, JP; Williams, TM Identification of a novel RAMP-independent CGRP receptor antagonist. Bioorg Med Chem Lett21:6705-8 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcitonin gene-related peptide 1 |
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| Name: | Calcitonin gene-related peptide 1 |
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| Synonyms: | CALC1 | CALCA | CALCA_HUMAN | CGRP | Calcitonin gene-related peptide (CGRP alpha) | Calcitonin gene-related peptide 1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 13902.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P06881 |
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| Residue: | 128 |
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| Sequence: | MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQ
MKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFG
RRRRDLQA
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| BDBM50356282 |
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| n/a |
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| Name | BDBM50356282 |
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| Synonyms: | CHEMBL1910936 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H29F2N5O3 |
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| Mol. Mass. | 557.5905 |
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| SMILES | Fc1cc(F)cc(c1)[C@@H]1CNC2(CCCC2)C(=O)N1CC(=O)Nc1ccc2C[C@]3(Cc2c1)C(=O)Nc1ncccc31 |r| |
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| Structure | 
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