| Reaction Details |
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 | Report a problem with these data |
| Target | Prostacyclin receptor |
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| Ligand | BDBM50351480 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_788407 (CHEMBL1918135) |
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| Ki | 3600±n/a nM |
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| Citation |  Iwahashi, M; Naganawa, A; Kinoshita, A; Shimabukuro, A; Nishiyama, T; Ogawa, S; Matsunaga, Y; Tsukamoto, K; Okada, Y; Matsumoto, R; Nambu, F; Oumi, R; Odagaki, Y; Katagi, J; Yano, K; Tani, K; Nakai, H; Toda, M Discovery of new orally active prostaglandin D2 receptor antagonists. Bioorg Med Chem19:6935-48 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostacyclin receptor |
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| Name: | Prostacyclin receptor |
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| Synonyms: | PGI receptor | PI2R_HUMAN | PRIPR | PTGIR | Prostacyclin (IP) Receptor | Prostacyclin receptor | Prostaglandin I | Prostaglandin I2 | Prostaglandin I2 receptor | Prostanoid IP receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40968.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | The membranes prepared from human platelet were used in binding assay. |
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| Residue: | 386 |
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| Sequence: | MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSARRPARPSAFAVLVTGLAATD
LLGTSFLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLA
LSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPG
GAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLIL
LALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVF
QRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPL
PPTQQSSGSAVGTSSKAEASVACSLC
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| BDBM50351480 |
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| n/a |
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| Name | BDBM50351480 |
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| Synonyms: | CHEMBL1819608 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H26N2O5 |
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| Mol. Mass. | 446.495 |
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| SMILES | CN1C[C@@H](COc2ccc(C(=O)Nc3cccc(CC(O)=O)c3)c(C)c2)Oc2ccccc12 |r| |
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| Structure | 
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