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TargetProstanoid DP receptor
LigandBDBM50351489
Substrate/Competitorn/a
Meas. Tech.ChEMBL_788406
Ki 7.7±n/a nM
Citation Iwahashi MNaganawa AKinoshita AShimabukuro ANishiyama TOgawa SMatsunaga YTsukamoto KOkada YMatsumoto RNambu FOumi ROdagaki YKatagi JYano KTani KNakai HToda M Discovery of new orally active prostaglandin D2 receptor antagonists. Bioorg Med Chem 19:6935-48 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostanoid DP receptor
Name:Prostanoid DP receptor
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:40018.63
Organism:Mus musculus
Description:ChEMBL_788408
Residue:357
Sequence:
MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVF
YVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTL
QLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGT
WCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSR
DRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSE
DLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50351489
n/a
NameBDBM50351489
Synonyms:CHEMBL1819614
TypeSmall organic molecule
Emp. Form.C26H25ClN2O5
Mol. Mass.480.94
SMILESCN1C[C@@H](COc2ccc(C(=O)Nc3cc(CC(O)=O)ccc3Cl)c(C)c2)Oc2ccccc12 |r|
Structure
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