| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin D2 receptor |
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| Ligand | BDBM50357635 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_788408 (CHEMBL1918136) |
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| IC50 | 0.7±n/a nM |
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| Citation |  Iwahashi, M; Naganawa, A; Kinoshita, A; Shimabukuro, A; Nishiyama, T; Ogawa, S; Matsunaga, Y; Tsukamoto, K; Okada, Y; Matsumoto, R; Nambu, F; Oumi, R; Odagaki, Y; Katagi, J; Yano, K; Tani, K; Nakai, H; Toda, M Discovery of new orally active prostaglandin D2 receptor antagonists. Bioorg Med Chem19:6935-48 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin D2 receptor |
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| Name: | Prostaglandin D2 receptor |
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| Synonyms: | PD2R_MOUSE | Prostanoid DP receptor | Ptgdr |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40018.63 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_788408 |
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| Residue: | 357 |
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| Sequence: | MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVF
YVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTL
QLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGT
WCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSR
DRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSE
DLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL
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| BDBM50357635 |
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| n/a |
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| Name | BDBM50357635 |
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| Synonyms: | CHEMBL1915863 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H31ClN2O5 |
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| Mol. Mass. | 523.02 |
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| SMILES | CN1C[C@@H](COc2cc(C)c(C(=O)Nc3cc(ccc3Cl)C(C)(C)C(O)=O)c(C)c2)Oc2ccccc12 |r| |
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| Structure | 
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