| Reaction Details |
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 | Report a problem with these data |
| Target | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog |
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| Ligand | BDBM21447 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_785797 (CHEMBL1920920) |
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| Kd | >1000±n/a nM |
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| Citation |  Goreshnik, I; Brock, AM; Maly, DJ Biochemical and pharmacological profiling of the pro-survival protein Bcl-xL. Bioorg Med Chem Lett21:4951-5 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Induced myeloid leukemia cell differentiation protein Mcl-1 homolog |
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| Name: | Induced myeloid leukemia cell differentiation protein Mcl-1 homolog |
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| Synonyms: | Bcl-2-related protein EAT/mcl1 | MCL1_MOUSE | Mcl-1 | Mcl1 |
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| Type: | Developmental protein |
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| Mol. Mass.: | 35215.08 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | n/a |
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| Residue: | 331 |
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| Sequence: | MFGLRRNAVIGLNLYCGGASLGAGGGSPAGARLVAEEAKARREGGGEAALLPGARVVARP
PPVGAEDPDVTASAERRLHKSPGLLAVPPEEMAASAAAAIVSPEEELDGCEPEAIGKRPA
VLPLLERVSEAAKSSGADGSLPSTPPPPEEEEDDLYRQSLEIISRYLREQATGSKDSKPL
GEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEGDVKSFSRVMVHVFKDGVT
NWGRIVTLISFGAFVAKHLKSVNQESFIEPLAETITDVLVRTKRDWLVKQRGWDGFVEFF
HVQDLEGGIRNVLLAFAGVAGVGAGLAYLIR
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| BDBM21447 |
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| n/a |
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| Name | BDBM21447 |
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| Synonyms: | 4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1-yl)-N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrobenzene)sulfonyl]benzamide | ABT-737 | CHEMBL376408 | N-Benylpiperazine derivative, 2 | US11760752, Compound ABT-737 | US9125913, ABT-737 |
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| Type | Small organic molecule |
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| Emp. Form. | C42H45ClN6O5S2 |
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| Mol. Mass. | 813.427 |
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| SMILES | CN(C)CC[C@H](CSc1ccccc1)Nc1ccc(cc1[N+]([O-])=O)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(Cc2ccccc2-c2ccc(Cl)cc2)CC1 |r| |
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| Structure | 
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