| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 |
|---|
| Ligand | BDBM50357881 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_787631 (CHEMBL1918084) |
|---|
| Kd | >5000±n/a nM |
|---|
| Citation |  Anraku, K; Inoue, T; Sugimoto, K; Kudo, K; Okamoto, Y; Morii, T; Mori, Y; Otsuka, M Design and synthesis of biotinylated inositol 1,3,4,5-tetrakisphosphate targeting Grp1 pleckstrin homology domain. Bioorg Med Chem19:6833-41 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 |
|---|
| Name: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 |
|---|
| Synonyms: | PLC-III | PLC-delta-1 | PLCD1_RAT | Phosphoinositide phospholipase C-delta-1 | Phospholipase C-III | Phospholipase C-delta-1 | Plcd1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 85958.21 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_787631 |
|---|
| Residue: | 756 |
|---|
| Sequence: | MDSGRDFLTLHGLQDDPDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKTIWQESRKVMR
SPESQLFSIEDIQEVRMGHRTEGLEKFARDIPEDRCFSIVFKDQRNTLDLIAPSPADAQH
WVQGLRKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQVDDGY
ARKIFRECDHSQTDSLEDEEIETFYKMLTQRAEIDRAFEEAAGSAETLSVERLVTFLQHQ
QREEEAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQDMDQ
PLSHYLVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTF
TSKILFCDVLRAIRDYAFKASPYPVILSLENHCSLEQQRVMARHLRAILGPILLDQPLDG
VTTSLPSPEQLKGKILLKGKKLGGLLPAGGENGSEATDVSDEVEAAEMEDEAVRSQVQHK
PKEDKLKLVPELSDMIIYCKSVHFGGFSSPGTSGQAFYEMASFSESRALRLLQESGNGFV
RHNVSCLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGCFQDNGGCG
YVLKPAFLRDPNTTFNSRALTQGPWWRPERLRVRIISGQQLPKVNKNKNSIVDPKVIVEI
HGVGRDTGSRQTAVITNNGFNPRWDMEFEFEVTVPDLALVRFMVEDYDSSSKNDFIGQST
IPWNSLKQGYRHVHLLSKNGDQHPSATLFVKISIQD
|
|
|
|---|
| BDBM50357881 |
|---|
| n/a |
|---|
| Name | BDBM50357881 |
|---|
| Synonyms: | CHEMBL1916340 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H43N3O20P4S |
|---|
| Mol. Mass. | 825.545 |
|---|
| SMILES | O[C@H]1[C@@H](OP(O)(=O)OCCCCCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1OP(O)(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
