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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Mast/stem cell growth factor receptor Kit | ||
| Ligand | BDBM50357884 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_786750 (CHEMBL1919591) | ||
| IC50 | >10000±n/a nM | ||
| Citation |  Lumeras, W; Vidal, L; Vidal, B; Balagué, C; Orellana, A; Maldonado, M; Domínguez, M; Segarra, V; Caturla, F 1,7-Naphthyridine 1-oxides as novel potent and selective inhibitors of p38 mitogen activated protein kinase. J Med Chem54:7899-910 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Mast/stem cell growth factor receptor Kit | |||
| Name: | Mast/stem cell growth factor receptor Kit | ||
| Synonyms: | CD117 antigen | CD_antigen=CD117 | KIT | KIT_HUMAN | Mast/stem cell growth factor receptor Kit (cKIT) | Proto-oncogene c-Kit | Proto-oncogene tyrosine-protein kinase Kit | SCFR | Stem cell growth factor receptor | Tyrosine Kinase c-Kit | Tyrosine-protein kinase Kit | Tyrosine-protein kinase Kit (c-Kit) | c-kit | p-145 c-kit | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | ||
| Type: | Protein | ||
| Mol. Mass.: | 109869.37 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P10721 | ||
| Residue: | 976 | ||
| Sequence: |
| ||
| BDBM50357884 | |||
| n/a | |||
| Name | BDBM50357884 | ||
| Synonyms: | CHEMBL1916359 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H10Cl3FN2O | ||
| Mol. Mass. | 419.664 | ||
| SMILES | [O-][n+]1ccc2c(ccnc2c1-c1c(Cl)cccc1Cl)-c1ccc(F)cc1Cl |(12.75,-22.82,;14.08,-22.05,;14.08,-20.51,;15.41,-19.74,;16.75,-20.5,;18.08,-19.73,;19.42,-20.51,;19.42,-22.05,;18.08,-22.82,;16.74,-22.05,;15.42,-22.83,;15.42,-24.36,;14.08,-25.13,;12.75,-24.36,;14.09,-26.67,;15.42,-27.44,;16.76,-26.66,;16.75,-25.12,;18.08,-24.34,;18.08,-18.2,;19.42,-17.43,;19.42,-15.89,;18.08,-15.12,;18.08,-13.58,;16.75,-15.89,;16.75,-17.43,;15.42,-18.2,)| | ||
| Structure | 
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