| Reaction Details |
|---|
 | Report a problem with these data |
| Target | NUAK family SNF1-like kinase 1 |
|---|
| Ligand | BDBM50358248 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_790768 (CHEMBL1926221) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Lai, D; Yu, S; van Ofwegen, L; Totzke, F; Proksch, P; Lin, W 9,10-secosteroids, protein kinase inhibitors from the Chinese gorgonian Astrogorgia sp. Bioorg Med Chem19:6873-80 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| NUAK family SNF1-like kinase 1 |
|---|
| Name: | NUAK family SNF1-like kinase 1 |
|---|
| Synonyms: | ARK5 | KIAA0537 | NUAK1 | NUAK1_HUMAN | OMPHK1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 74326.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1451343 |
|---|
| Residue: | 661 |
|---|
| Sequence: | MEGAAAPVAGDRPDLGLGAPGSPREAVAGATAALEPRKPHGVKRHHHKHNLKHRYELQET
LGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYE
VFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLK
LENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALG
VLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPSDARGLIRWMLMVNPDRRATIEDI
ANHWWVNWGYKSSVCDCDALHDSESPLLARIIDWHHRSTGLQADTEAKMKGLAKPTTSEV
MLERQRSLKKSKKENDFAQSGQDAVPESPSKLSSKRPKGILKKRSNSEHRSHSTGFIEGV
VGPALPSTFKMEQDLCRTGVLLPSSPEAEVPGKLSPKQSATMPKKGILKKTQQRESGYYS
SPERSESSELLDSNDVMGSSIPSPSPPDPARVTSHSLSCRRKGILKHSSKYSAGTMDPAL
VSPEMPTLESLSEPGVPAEGLSRSYSRPSSVISDDSVLSSDSFDLLDLQENRPARQRIRS
CVSAENFLQIQDFEGLQNRPRPQYLKRYRNRLADSSFSLLTDMDDVTQVYKQALEICSKL
N
|
|
|
|---|
| BDBM50358248 |
|---|
| n/a |
|---|
| Name | BDBM50358248 |
|---|
| Synonyms: | CHEMBL456294 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H42O3 |
|---|
| Mol. Mass. | 414.6206 |
|---|
| SMILES | CC(C)CCC[C@@H](C)[C@H]1[C@@H](O)C[C@H]2[C@H](CCc3cc(O)ccc3C)C(=O)CC[C@]12C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
