| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division protein FtsZ |
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| Ligand | BDBM50359401 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_793371 (CHEMBL1931925) |
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| IC50 | 34300±n/a nM |
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| Citation |  Mathew, B; Srivastava, S; Ross, LJ; Suling, WJ; White, EL; Woolhiser, LK; Lenaerts, AJ; Reynolds, RC Novel pyridopyrazine and pyrimidothiazine derivatives as FtsZ inhibitors. Bioorg Med Chem19:7120-8 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cell division protein FtsZ |
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| Name: | Cell division protein FtsZ |
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| Synonyms: | FTSZ_MYCTU | ftsZ |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38736.30 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | ChEMBL_1470459 |
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| Residue: | 379 |
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| Sequence: | MTPPHNYLAVIKVVGIGGGGVNAVNRMIEQGLKGVEFIAINTDAQALLMSDADVKLDVGR
DSTRGLGAGADPEVGRKAAEDAKDEIEELLRGADMVFVTAGEGGGTGTGGAPVVASIARK
LGALTVGVVTRPFSFEGKRRSNQAENGIAALRESCDTLIVIPNDRLLQMGDAAVSLMDAF
RSADEVLLNGVQGITDLITTPGLINVDFADVKGIMSGAGTALMGIGSARGEGRSLKAAEI
AINSPLLEASMEGAQGVLMSIAGGSDLGLFEINEAASLVQDAAHPDANIIFGTVIDDSLG
DEVRVTVIAAGFDVSGPGRKPVMGETGGAHRIESAKAGKLTSTLFEPVDAVSVPLHTNGA
TLSIGGDDDDVDVPPFMRR
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| BDBM50359401 |
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| n/a |
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| Name | BDBM50359401 |
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| Synonyms: | CHEMBL1929426 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H34N6O2S2 |
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| Mol. Mass. | 538.728 |
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| SMILES | CCOC(=O)Nc1cc(NC(C)CCCN(CC)CC)c2nc(-c3cccs3)c(nc2n1)-c1cccs1 |
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| Structure | 
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