Reaction Details |
| Report a problem with these data |
Target | Sigma non-opioid intracellular receptor 1 |
---|
Ligand | BDBM50419548 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_792210 (CHEMBL1930737) |
---|
Ki | 0.38±n/a nM |
---|
Citation | Ferorelli, S; Abate, C; Pedone, MP; Colabufo, NA; Contino, M; Perrone, R; Berardi, F Synthesis and binding assays of novel 3,3-dimethylpiperidine derivatives with various lipophilicities ass¿? receptor ligands. Bioorg Med Chem19:7612-22 (2011) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Sigma non-opioid intracellular receptor 1 |
---|
Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
Type: | Protein |
Mol. Mass.: | 25307.17 |
Organism: | Cavia porcellus (Guinea pig) |
Description: | Q60492 |
Residue: | 223 |
Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
|
|
|
BDBM50419548 |
---|
n/a |
---|
Name | BDBM50419548 |
Synonyms: | CHEMBL1929281 |
Type | Small organic molecule |
Emp. Form. | C21H33N |
Mol. Mass. | 299.4934 |
SMILES | CC1(C)CCCN(CCCC2CCCCc3ccccc23)C1 |
Structure |
|