| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP4 subtype |
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| Ligand | BDBM50360166 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_793560 (CHEMBL1932311) |
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| Ki | 2±n/a nM |
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| Citation |  Kambe, T; Maruyama, T; Nagase, T; Ogawa, S; Minamoto, C; Sakata, K; Maruyama, T; Nakai, H; Toda, M Synthesis and evaluation of novel modified¿-lactam prostanoids as EP4 subtype-selective agonists. Bioorg Med Chem20:702-13 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP4 subtype |
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| Name: | Prostaglandin E2 receptor EP4 subtype |
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| Synonyms: | PE2R4_MOUSE | PGE receptor, EP4 subtype | Prostanoid EP4 receptor | Ptger4 | Ptgerep4 |
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| Type: | G-protein coupled receptor |
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| Mol. Mass.: | 56175.66 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | n/a |
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| Residue: | 513 |
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| Sequence: | MAEVGGTIPRSNRELQRCVLLTTTIMSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGN
LVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYS
TFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAIYASNVLFCALPN
MGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMHR
QFMRRTSLGTEQHHAAAAAAVASVACRGHAGASPALQRLSDFRRRRSFRRIAGAEIQMVI
LLIATSLVVLICSIPLVVRVFINQLYQPNVVKDISRNPDLQAIRIASVNPILDPWIYILL
RKTVLSKAIEKIKCLFCRIGGSGRDSSAQHCSESRRTSSAMSGHSRSFLARELKEISSTS
QTLLYLPDLTESSLGGRNLLPGSHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVD
EVSGSHREEPASKGNSLQVTFPSETLKLSEKCI
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| BDBM50360166 |
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| n/a |
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| Name | BDBM50360166 |
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| Synonyms: | CHEMBL1929533 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24F3NO5S |
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| Mol. Mass. | 447.468 |
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| SMILES | O[C@@H](Cc1cccc(c1)C(F)(F)F)\C=C\[C@H]1COC(=O)N1CCSCCCC(O)=O |r| |
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| Structure | 
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