| Reaction Details |
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 | Report a problem with these data |
| Target | Glucagon receptor |
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| Ligand | BDBM50360587 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_795440 (CHEMBL1937445) |
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| Ki | 968±n/a nM |
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| Citation |  Filipski, KJ; Bian, J; Ebner, DC; Lee, EC; Li, JC; Sammons, MF; Wright, SW; Stevens, BD; Didiuk, MT; Tu, M; Perreault, C; Brown, J; Atkinson, K; Tan, B; Salatto, CT; Litchfield, J; Pfefferkorn, JA; Guzman-Perez, A A novel series of glucagon receptor antagonists with reduced molecular weight and lipophilicity. Bioorg Med Chem Lett22:415-20 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucagon receptor |
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| Name: | Glucagon receptor |
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| Synonyms: | GCGR | GL-R | GLR_HUMAN | Glucagon Receptor (GCGR) | Glucagon receptor (GlucR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 54026.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47871 |
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| Residue: | 477 |
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| Sequence: | MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNR
TFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQ
CQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANL
FASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYC
WLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDN
MGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGV
HEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRL
GKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF
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| BDBM50360587 |
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| n/a |
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| Name | BDBM50360587 |
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| Synonyms: | CHEMBL1933353 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H27N3O4 |
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| Mol. Mass. | 421.4889 |
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| SMILES | CCCC(Oc1cnn(c1)-c1ccc(C)cc1)c1ccc(cc1)C(=O)NCCC(O)=O |
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| Structure | 
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