| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 1 |
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| Ligand | BDBM50361038 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_796042 (CHEMBL1936575) |
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| EC50 | 4±n/a nM |
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| Citation |  Kurata, H; Kusumi, K; Otsuki, K; Suzuki, R; Kurono, M; Tokuda, N; Takada, Y; Shioya, H; Mizuno, H; Komiya, T; Ono, T; Hagiya, H; Minami, M; Nakade, S; Habashita, H Structure-activity relationship studies of S1P agonists with a dihydronaphthalene scaffold. Bioorg Med Chem Lett22:144-8 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 1 |
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| Name: | Sphingosine 1-phosphate receptor 1 |
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| Synonyms: | CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42836.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21453 |
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| Residue: | 382 |
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| Sequence: | MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
PQKDEGDNPETIMSSGNVNSSS
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| BDBM50361038 |
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| n/a |
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| Name | BDBM50361038 |
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| Synonyms: | CHEMBL1935577 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H28FNO3 |
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| Mol. Mass. | 409.4931 |
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| SMILES | CC1=C(CN2CC(C2)C(O)=O)CCc2cc(OCCCc3cccc(F)c3)ccc12 |c:1| |
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| Structure | 
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