| Reaction Details |
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 | Report a problem with these data |
| Target | Hypoxia-inducible factor 1-alpha inhibitor |
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| Ligand | BDBM50361473 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_797225 (CHEMBL1942540) |
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| IC50 | 21000±n/a nM |
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| Citation |  Suzuki, T; Miyata, N Lysine demethylases inhibitors. J Med Chem54:8236-50 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Hypoxia-inducible factor 1-alpha inhibitor |
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| Name: | Hypoxia-inducible factor 1-alpha inhibitor |
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| Synonyms: | FIH1 | HIF1AN | HIF1N_HUMAN | Hypoxia-inducible factor 1 (FIH) | Hypoxia-inducible factor 1-alpha inhibitor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40278.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9NWT6 |
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| Residue: | 349 |
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| Sequence: | MAATAAEAVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEE
PVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNR
EEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWG
QLTSNLLLIGMEGNVTPAHYDEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQS
QVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGA
PTPKRIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYN
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| BDBM50361473 |
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| n/a |
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| Name | BDBM50361473 |
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| Synonyms: | CHEMBL1435274 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H7NO3 |
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| Mol. Mass. | 189.1675 |
|---|
| SMILES | OC(=O)c1ccnc2c(O)cccc12 |
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| Structure | 
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