| Reaction Details |
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 | Report a problem with these data |
| Target | Glutathione S-transferase Mu 1 |
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| Ligand | BDBM50361800 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_799591 (CHEMBL1941297) |
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| IC50 | 13400±n/a nM |
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| Citation |  Wang, CH; Wu, HT; Cheng, HM; Yen, TJ; Lu, IH; Chang, HC; Jao, SC; Shing, TK; Li, WS Inhibition of glutathione S-transferase M1 by new gabosine analogues is essential for overcoming cisplatin resistance in lung cancer cells. J Med Chem54:8574-81 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutathione S-transferase Mu 1 |
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| Name: | Glutathione S-transferase Mu 1 |
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| Synonyms: | GST class-mu 1 | GST1 | GSTM1 | GSTM1-1 | GSTM1_HUMAN | GSTM1a-1a | GSTM1b-1b | GTH4 | Glutathione S-transferase Mu 1 | HB subunit 4 | glutathione S-transferase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25712.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_799596 |
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| Residue: | 218 |
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| Sequence: | MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN
LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
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| BDBM50361800 |
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| n/a |
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| Name | BDBM50361800 |
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| Synonyms: | CHEMBL1938641 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H32O6 |
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| Mol. Mass. | 356.4538 |
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| SMILES | CCCCCCCCCCO[C@H]1CC(COC(C)=O)C(=O)C(=O)[C@H]1O |r| |
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| Structure | 
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