| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 1 |
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| Ligand | BDBM50361926 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_800100 (CHEMBL1941991) |
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| EC50 | 2000±n/a nM |
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| Citation |  Ukani, R; Lewis, TC; Day, TP; Wu, W; Malladi, SS; Warshakoon, HJ; David, SA Potent adjuvantic activity of a CCR1-agonistic bis-quinoline. Bioorg Med Chem Lett22:293-5 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 1 |
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| Name: | C-C chemokine receptor type 1 |
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| Synonyms: | C-C CKR-1 | C-C chemokine receptor type 1 (CCR1) | CC-CKR-1 | CCR-1 | CCR1 | CCR1_HUMAN | CD_antigen=CD191 | CMKBR1 | CMKR1 | HM145 | LD78 receptor | MIP-1alpha-R | Macrophage inflammatory protein 1-alpha receptor | RANTES-R | SCYAR1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41180.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P32246 |
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| Residue: | 355 |
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| Sequence: | METPNTTEDYDTTTEFDYGDATPCQKVNERAFGAQLLPPLYSLVFVIGLVGNILVVLVLV
QYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGFYYTGLYSE
IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYFSKTQWEFTH
HTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLRRPNEKKSKAVRL
IFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQVTEVIAYTHCCVNPVI
YAFVGERFRKYLRQLFHRRVAVHLVKWLPFLSVDRLERVSSTSPSTGEHELSAGF
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| BDBM50361926 |
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| n/a |
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| Name | BDBM50361926 |
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| Synonyms: | CHEMBL66165 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20Cl2N4 |
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| Mol. Mass. | 411.327 |
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| SMILES | Clc1ccc2c(NCCCCNc3ccnc4cc(Cl)ccc34)ccnc2c1 |
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| Structure | 
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