| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50361998 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_799943 (CHEMBL1941649) |
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| Ki | 0.740000±n/a nM |
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| Citation |  Maisonial, A; Grosse Maestrup, E; Wiese, C; Hiller, A; Schepmann, D; Fischer, S; Deuther-Conrad, W; Steinbach, J; Brust, P; Wünsch, B Synthesis, radiofluorination and pharmacological evaluation of a fluoromethyl spirocyclic PET tracer for centrals1 receptors and comparison with fluoroalkyl homologs. Bioorg Med Chem20:257-69 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50361998 |
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| n/a |
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| Name | BDBM50361998 |
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| Synonyms: | CHEMBL1939698 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22FNO |
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| Mol. Mass. | 311.3932 |
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| SMILES | FCC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc12 |
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| Structure | 
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