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TargetNeuropeptides B/W receptor type 1
LigandBDBM50362419
Substrate/Competitorn/a
Meas. Tech.ChEMBL_797950 (CHEMBL1942827)
IC50 0.2±n/a nM
Citation Anthony Romero, FHastings, NBMoningka, RGuo, ZWang, MDi Salvo, JLei, YTrusca, DDeng, QTong, VTerebetski, JLBall, RGUjjainwalla, F The discovery of potent antagonists of NPBWR1 (GPR7). Bioorg Med Chem Lett22:1014-8 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Neuropeptides B/W receptor type 1
Name:Neuropeptides B/W receptor type 1
Synonyms:G-protein coupled receptor 7 | Gpr7 | NPBW1_MOUSE | Npbwr1
Type:PROTEIN
Mol. Mass.:36085.77
Organism:Mus musculus
Description:ChEMBL_797950
Residue:329
Sequence:
MHNLTLFESGGDNVSCGGSSLGCPNGSSLAPLPLPQPLAVAVPVVYGVICAVGLAGNSAV
LYVLLRTPRMKTVTNVFILNLAIADELFTLVLPINIADFLLRRWPFGEVMCKLIVAVDQY
NTFSSLYFLAVMSADRYLVVLATAESRRVSGRTYGAARAVSLAVWALVTLVVLPFAVFAR
LDEEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVTTICALYTTLLCRLRAIQLDSH
AKALDRAKKRVTLLVAAILAVCLLCWTPYHLSTIVALTTDLPQTPLVIGISYFITSLSYA
NSCLNPFLYAFLDDSFRRSLRQLVSCRSA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50362419
n/a
NameBDBM50362419
Synonyms:CHEMBL1940544
TypeSmall organic molecule
Emp. Form.C33H37FN4O3S
Mol. Mass.588.735
SMILESCOc1ccc(cc1)C1(CCC1)N[C@@H]1CC[C@@H]([C@H](C1)c1ccsc1)C(=O)N1CCN(CC1)c1nc2cc(F)ccc2o1 |r|
Structure
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