| Reaction Details |
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 | Report a problem with these data |
| Target | 2-dehydro-3-deoxyphosphooctonate aldolase |
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| Ligand | BDBM50281349 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_797884 (CHEMBL1942571) |
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| Ki | 260000±n/a nM |
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| Citation |  Harrison, AN; Reichau, S; Parker, EJ Synthesis and evaluation of tetrahedral intermediate mimic inhibitors of 3-deoxy-d-manno-octulosonate 8-phosphate synthase. Bioorg Med Chem Lett22:907-11 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 2-dehydro-3-deoxyphosphooctonate aldolase |
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| Name: | 2-dehydro-3-deoxyphosphooctonate aldolase |
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| Synonyms: | 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase | KDO 8-P synthase | KDO-8-phosphate synthase | KDOPS | KDSA_NEIMB | Phospho-2-dehydro-3-deoxyoctonate aldolase | kdsA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30484.01 |
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| Organism: | Neisseria meningitidis serogroup B (strain MC58) |
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| Description: | ChEMBL_797884 |
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| Residue: | 280 |
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| Sequence: | MDIKINDITLGNNSPFVLFGGINVLESLDSTLQTCAHYVEVTRKLGIPYIFKASFDKANR
SSIHSYRGVGLEEGLKIFEKVKAEFGIPVITDVHEPHQCQPVAEVCDVIQLPAFLARQTD
LVVAMAKTGNVVNIKKPQFLSPSQMKNIVEKFHEAGNGKLILCERGSSFGYDNLVVDMLG
FGVMKQTCGNLPVIFDVTHSLQTRDAGSAASGGRRAQALDLALAGMATRLAGLFLESHPD
PKLAKCDGPSALPLHLLEDFLIRIKALDDLIKSQPILTIE
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| BDBM50281349 |
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| n/a |
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| Name | BDBM50281349 |
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| Synonyms: | CHEMBL95764 | N-(phosphonomethyl)glycine | glyphosate |
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| Type | Small organic molecule |
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| Emp. Form. | C3H8NO5P |
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| Mol. Mass. | 169.0731 |
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| SMILES | OC(=O)CNCP(O)(O)=O |
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| Structure | 
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