| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50293031 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_800443 (CHEMBL1948464) |
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| Ki | 1±n/a nM |
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| Citation |  Hou, X; Majik, MS; Kim, K; Pyee, Y; Lee, Y; Alexander, V; Chung, HJ; Lee, HW; Chandra, G; Lee, JH; Park, SG; Choi, WJ; Kim, HO; Phan, K; Gao, ZG; Jacobson, KA; Choi, S; Lee, SK; Jeong, LS Structure-activity relationships of truncated C2- or C8-substituted adenosine derivatives as dual acting A2A and A3 adenosine receptor ligands. J Med Chem55:342-56 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50293031 |
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| n/a |
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| Name | BDBM50293031 |
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| Synonyms: | 2-chloro-N6-(3-iodobenzyl)-5'-N-methylcarbamoyladenosine | 2-chloro-N6-(3-iodobenzyl)adenosine-5'-N-methylcarboxamide | CHEMBL515442 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20ClIN6O5 |
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| Mol. Mass. | 574.757 |
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| SMILES | CNC(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3cccc(I)c3)nc(Cl)nc12 |r| |
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| Structure | 
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