| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 4 |
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| Ligand | BDBM50363969 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_803952 (CHEMBL1954783) |
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| IC50 | 4±n/a nM |
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| Citation |  Demmer, O; Dijkgraaf, I; Schumacher, U; Marinelli, L; Cosconati, S; Gourni, E; Wester, HJ; Kessler, H Design, synthesis, and functionalization of dimeric peptides targeting chemokine receptor CXCR4. J Med Chem54:7648-62 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 4 |
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| Name: | C-X-C chemokine receptor type 4 |
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| Synonyms: | C-X-C chemokine receptor type 4 | C-X-C chemokine receptor type 4 (CXCR4) | CD_antigen=CD184 | CXC-R4 | CXCR-4 | CXCR4 | CXCR4_HUMAN | FB22 | Fusin | HM89 | LCR1 | LESTR | Leukocyte-derived seven transmembrane domain receptor | NPYRL | SDF-1 receptor | Stromal cell-derived factor 1 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 39754.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P61073 |
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| Residue: | 352 |
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| Sequence: | MEGISIYTSDNYTEEMGSGDYDSMKEPCFREENANFNKIFLPTIYSIIFLTGIVGNGLVI
LVMGYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAVANWYFGNFLCKAVHVIYTVNL
YSSVLILAFISLDRYLAIVHATNSQRPRKLLAEKVVYVGVWIPALLLTIPDFIFANVSEA
DDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKT
TVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPI
LYAFLGAKFKTSAQHALTSVSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
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| BDBM50363969 |
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| n/a |
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| Name | BDBM50363969 |
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| Synonyms: | CHEMBL1949734 |
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| Type | Small organic molecule |
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| Emp. Form. | C77H98N18O14 |
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| Mol. Mass. | 1499.7142 |
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| SMILES | [#6]-[#7]-1-[#6@H](-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-[#6]-[#6]-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6@H]-2-[#7](-[#6])-[#6](=O)-[#6@@H](-[#6]-c3ccc(-[#8])cc3)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-c3ccc4ccccc4c3)-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6]-2=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c2ccc3ccccc3c2)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@H](-[#6]-c2ccc(-[#8])cc2)-[#6]-1=O |r| |
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| Structure | 
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