| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Legumain |
|---|
| Ligand | BDBM50364359 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_805028 (CHEMBL1952889) |
|---|
| IC50 | 638±n/a nM |
|---|
| Citation |  Lee, J; Bogyo, M Synthesis and evaluation of aza-peptidyl inhibitors of the lysosomal asparaginyl endopeptidase, legumain. Bioorg Med Chem Lett22:1340-3 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Legumain |
|---|
| Name: | Legumain |
|---|
| Synonyms: | LGMN_MOUSE | Lgmn | Prsc1 | asparaginyl endopeptidase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 49370.42 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | n/a |
|---|
| Residue: | 435 |
|---|
| Sequence: | MTWRVAVLLSLVLGAGAVPVGVDDPEDGGKHWVVIVAGSNGWYNYRHQADACHAYQIIHR
NGIPDEQIIVMMYDDIANSEENPTPGVVINRPNGTDVYKGVLKDYTGEDVTPENFLAVLR
GDAEAVKGKGSGKVLKSGPRDHVFIYFTDHGATGILVFPNDDLHVKDLNKTIRYMYEHKM
YQKMVFYIEACESGSMMNHLPDDINVYATTAANPKESSYACYYDEERGTYLGDWYSVNWM
EDSDVEDLTKETLHKQYHLVKSHTNTSHVMQYGNKSISTMKVMQFQGMKHRASSPISLPP
VTHLDLTPSPDVPLTILKRKLLRTNDVKESQNLIGQIQQFLDARHVIEKSVHKIVSLLAG
FGETAERHLSERTMLTAHDCYQEAVTHFRTHCFNWHSVTYEHALRYLYVLANLCEAPYPI
DRIEMAMDKVCLSHY
|
|
|
|---|
| BDBM50364359 |
|---|
| n/a |
|---|
| Name | BDBM50364359 |
|---|
| Synonyms: | CHEMBL1950274 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H31N5O7 |
|---|
| Mol. Mass. | 465.5001 |
|---|
| SMILES | CCOC(=O)\C=C\C(=O)N(CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H]1CCCCN1C(C)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
