| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin D2 receptor 2 |
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| Ligand | BDBM50364528 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_802808 (CHEMBL1953542) |
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| IC50 | 2±n/a nM |
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| Citation |  Liu, JJ; Wang, Y; Johnson, MG; Li, AR; Shen, W; Wang, X; Su, Y; Brown, M; Van Lengerich, B; Rickel, E; Martin, T; Budelsky, A; Seitz, L; Danao, J; Tang, HL; Collins, T; Medina, JC Optimization of phenylacetic acid derivatives for balanced CRTH2 and DP dual antagonists. Bioorg Med Chem Lett22:1686-9 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin D2 receptor 2 |
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| Name: | Prostaglandin D2 receptor 2 |
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| Synonyms: | CD_antigen=CD294 | CRTH2 | Chemoattractant Receptor-homologous molecule expressed on T-helper type 2 cells (CRTH2) | Chemoattractant receptor-homologous molecule expressed on Th2 cells | Chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) | DL1R | G protein-coupled receptor 44 | G-protein coupled receptor 44 | GPR44 | PD2R2_HUMAN | PTGDR2 | Prostaglandin D2 | Prostaglandin D2 receptor 2 | Prostaglandin D2 receptor 2 (PGD2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 43295.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y5Y4 |
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| Residue: | 395 |
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| Sequence: | MSANATLKPLCPILEQMSRLQSHSNTSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCR
MRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGF
LLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRI
MCYYNVLLLNPGPDRDATCNSRQVALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRGRRR
PGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVAN
PVLYVLTCPDMLRKLRRSLRTVLESVLVDDSELGGAGSSRRRRTSSTARSASPLALCSRP
EEPRGPARLLGWLLGSCAASPQTGPLNRALSSTSS
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| BDBM50364528 |
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| n/a |
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| Name | BDBM50364528 |
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| Synonyms: | CHEMBL1950871 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H28Cl2N2O6S |
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| Mol. Mass. | 579.492 |
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| SMILES | CCCCNC(=O)c1ccc(Cc2ccc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 |
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| Structure | 
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