| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Fibroblast growth factor receptor 2 |
|---|
| Ligand | BDBM50364832 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_803518 (CHEMBL1953266) |
|---|
| IC50 | >50000±n/a nM |
|---|
| Citation |  Hada, K; Suda, A; Asoh, K; Tsukuda, T; Hasegawa, M; Sato, Y; Ogawa, K; Kuramoto, S; Aoki, Y; Shimma, N; Ishikawa, T; Koyano, H Angiogenesis inhibitors identified by cell-based high-throughput screening: synthesis, structure-activity relationships and biological evaluation of 3-[(E)-styryl]benzamides that specifically inhibit endothelial cell proliferation. Bioorg Med Chem20:1442-60 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Fibroblast growth factor receptor 2 |
|---|
| Name: | Fibroblast growth factor receptor 2 |
|---|
| Synonyms: | BEK | CD_antigen=CD332 | FGFR-2 | FGFR-2 Tyrosine Kinase | FGFR2 | FGFR2_HUMAN | Fibroblast growth factor receptor 2 (FGFR2) | Fibroblast growth factor receptor 2 precursor | KGFR | KSAM | Keratinocyte growth factor receptor | Keratinocyte growth factor receptor 2 | VEGF-receptor 2 and Fibroblast growth factor receptor 2 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 92015.45 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21802 |
|---|
| Residue: | 821 |
|---|
| Sequence: | MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEV
RCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYF
MVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCP
AGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSI
NHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSK
YGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVL
PAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTK
RIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDK
LTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKM
IGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTF
KDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKT
TNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGH
RMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYS
PSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT
|
|
|
|---|
| BDBM50364832 |
|---|
| n/a |
|---|
| Name | BDBM50364832 |
|---|
| Synonyms: | CHEMBL1949788 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H20ClNO4 |
|---|
| Mol. Mass. | 361.819 |
|---|
| SMILES | COc1ccc(cc1\C=C\c1ccc(Cl)cc1)C(=O)NC[C@@H](O)CO |r| |
|---|
| Structure | 
|
|---|
Search and Browse
