Reaction Details |
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Target | 5-hydroxytryptamine receptor 6 |
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Ligand | BDBM50364980 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_804508 (CHEMBL1952518) |
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Ki | 0.370±n/a nM |
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Citation | Henderson, AJ; Guzzo, PR; Ghosh, A; Kaur, J; Koo, JM; Nacro, K; Panduga, S; Pathak, R; Shimpukade, B; Tan, V; Xiang, K; Wierschke, JD; Isherwood, ML Epiminocyclohepta[b]indole analogs as 5-HT6 antagonists. Bioorg Med Chem Lett22:1494-8 (2012) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 6 |
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Name: | 5-hydroxytryptamine receptor 6 |
Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 46968.43 |
Organism: | Homo sapiens (Human) |
Description: | P50406 |
Residue: | 440 |
Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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BDBM50364980 |
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n/a |
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Name | BDBM50364980 |
Synonyms: | CHEMBL1950775 |
Type | Small organic molecule |
Emp. Form. | C22H21N3O2S |
Mol. Mass. | 391.486 |
SMILES | Cn1c2CC3CCC(N3)c2c2cc(ccc12)S(=O)(=O)c1ccc2[nH]ccc2c1 |
Structure |
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