| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM25392 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_804869 (CHEMBL1953787) |
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| EC50 | 31.62±n/a nM |
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| Citation |  Shan, WJ; Huang, L; Zhou, Q; Jiang, HL; Luo, ZH; Lai, KF; Li, XS Dualß2-adrenoceptor agonists-PDE4 inhibitors for the treatment of asthma and COPD. Bioorg Med Chem Lett22:1523-6 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2_CAVPO | Adrb2 | adrenergic Beta2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46993.24 |
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| Organism: | GUINEA PIG |
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| Description: | adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4 |
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| Residue: | 418 |
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| Sequence: | MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKD
AINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRF
HTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNG
KTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
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| BDBM25392 |
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| n/a |
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| Name | BDBM25392 |
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| Synonyms: | 4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride | 4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol | 4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol, 2 | CHEMBL434 | ISOPROTERONOL | Isoprenaline | Isoproterenol | Isoproterenol (-) | Isoproterenol,(+) | Isoproterenol-l | Norisodrine | Novodrin |
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| Type | Small organic molecule |
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| Emp. Form. | C11H17NO3 |
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| Mol. Mass. | 211.2576 |
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| SMILES | CC(C)NCC(O)c1ccc(O)c(O)c1 |
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| Structure | 
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