| Reaction Details |
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 | Report a problem with these data |
| Target | Eukaryotic translation initiation factor 4E |
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| Ligand | BDBM50365103 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_804894 (CHEMBL1953942) |
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| IC50 | 5000±n/a nM |
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| Citation |  Rydzik, AM; Kulis, M; Lukaszewicz, M; Kowalska, J; Zuberek, J; Darzynkiewicz, ZM; Darzynkiewicz, E; Jemielity, J Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety--fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis. Bioorg Med Chem20:1699-710 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Eukaryotic translation initiation factor 4E |
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| Name: | Eukaryotic translation initiation factor 4E |
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| Synonyms: | EIF4E | IF4E_RABIT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25047.40 |
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| Organism: | Oryctolagus cuniculus |
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| Description: | ChEMBL_1511842 |
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| Residue: | 217 |
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| Sequence: | MATVEPETTPTPNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANL
RLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQ
QRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIG
RVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
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| BDBM50365103 |
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| n/a |
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| Name | BDBM50365103 |
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| Synonyms: | CHEMBL1951189 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26N10O21P4 |
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| Mol. Mass. | 878.3828 |
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| SMILES | C[n+]1cn([C@@H]2O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n3cnc4c3nc(N)[nH]c4=O)[C@@H](O)[C@H]2O)c2nc(N)[n-]c(=O)c12 |r| |
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| Structure | 
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