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TargetCyclin-dependent kinase 2
LigandBDBM50026854
Substrate/Competitorn/a
Meas. Tech.ChEMBL_807302 (CHEMBL1960395)
IC50<15849±n/a nM
Citation Gentile, GMerlo, GPozzan, ABernasconi, GBax, BBamborough, PBridges, ACarter, PNeu, MYao, GBrough, CCutler, GCoffin, ABelyanskaya, S 5-Aryl-4-carboxamide-1,3-oxazoles: potent and selective GSK-3 inhibitors. Bioorg Med Chem Lett22:1989-94 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cyclin-dependent kinase 2
Name:Cyclin-dependent kinase 2
Synonyms:CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase
Type:Enzyme Subunit
Mol. Mass.:33938.17
Organism:Homo sapiens (Human)
Description:P24941
Residue:298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
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  Blast E-value cutoff:
BDBM50026854
n/a
NameBDBM50026854
Synonyms:CHEMBL1957094
TypeSmall organic molecule
Emp. Form.C18H17N3O3
Mol. Mass.323.3459
SMILESCOc1ccc(-c2ocnc2C(=O)NCc2ccncc2)c(C)c1
Structure
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