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TargetMu-type opioid receptor
LigandBDBM50365853
Substrate/Competitorn/a
Meas. Tech.ChEMBL_806706
Ki 0.81±n/a nM
Citation Lunn GRoberts LRContent SCritcher DJDouglas SFenwick AEGethin DMGoodwin GGreenway DGreenwood SHall KThomas MThompson SWilliams DWood GWylie A SAR and biological evaluation of 3-azabicyclo[3.1.0]hexane derivatives asµ opioid ligands. Bioorg Med Chem Lett 22:2200-3 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Cannabinoid receptor 1/Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50365853
n/a
NameBDBM50365853
Synonyms:CHEMBL1957717
TypeSmall organic molecule
Emp. Form.C23H28N2O2S
Mol. Mass.396.546
SMILESC[C@]1([C@H]2CN(CC3Cc4ccccc4C3)C[C@@H]12)c1cccc(NS(C)(=O)=O)c1 |r|
Structure
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