| Reaction Details |
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 | Report a problem with these data |
| Target | Vasoactive intestinal polypeptide receptor 1 |
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| Ligand | BDBM50241256 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_807309 (CHEMBL1960402) |
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| IC50 | 15000±n/a nM |
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| Citation |  Harikrishnan, LS; Srivastava, N; Kayser, LE; Nirschl, DS; Kumaragurubaran, K; Roy, A; Gupta, A; Karmakar, S; Karatt, T; Mathur, A; Burford, NT; Chen, J; Kong, Y; Cvijic, M; Cooper, CB; Poss, MA; Trainor, GL; Wong, TW Identification and optimization of small molecule antagonists of vasoactive intestinal peptide receptor-1 (VIPR1). Bioorg Med Chem Lett22:2287-90 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasoactive intestinal polypeptide receptor 1 |
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| Name: | Vasoactive intestinal polypeptide receptor 1 |
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| Synonyms: | PACAP type II receptor | PACAP-R-2 | PACAP-R2 | Pituitary adenylate cyclase-activating polypeptide type II receptor | VIP-R-1 | VIPR1_RAT | Vipr1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 52068.73 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_807309 |
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| Residue: | 459 |
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| Sequence: | MRPPSPPHVRWLCVLAGALACALRPAGSQAASPQHECEYLQLIEIQRQQCLEEAQLENET
TGCSKMWDNLTCWPTTPRGQAVVLDCPLIFQLFAPIHGYNISRSCTEEGWSQLEPGPYHI
ACGLNDRASSLDEQQQTKFYNTVKTGYTIGYSLSLASLLVAMAILSLFRKLHCTRNYIHM
HLFMSFILRATAVFIKDMALFNSGEIDHCSEASVGCKAAVVFFQYCVMANFFWLLVEGLY
LYTLLAVSFFSERKYFWGYILIGWGVPSVFITIWTVVRIYFEDFGCWDTIINSSLWWIIK
APILLSILVNFVLFICIIRILVQKLRPPDIGKNDSSPYSRLAKSTLLLIPLFGIHYVMFA
FFPDNFKAQVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWSSKS
QHPWGGSNGATCSTQVSMLTRVSPSARRSSSFQAEVSLV
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| BDBM50241256 |
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| n/a |
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| Name | BDBM50241256 |
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| Synonyms: | CHEMBL233000 | N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C16H14N2OS |
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| Mol. Mass. | 282.36 |
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| SMILES | O=C(Nc1sc2CCCCc2c1C#N)c1ccccc1 |
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| Structure | 
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