| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
|---|
| Ligand | BDBM50366034 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_807332 (CHEMBL1960512) |
|---|
| Ki | 420±n/a nM |
|---|
| Citation |  Carta, F; Vullo, D; Maresca, A; Scozzafava, A; Supuran, CT New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II. Bioorg Med Chem Lett22:2182-5 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 7 |
|---|
| Name: | Carbonic anhydrase 7 |
|---|
| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29664.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Human cloned isozyme. |
|---|
| Residue: | 264 |
|---|
| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
|
|
|
|---|
| BDBM50366034 |
|---|
| n/a |
|---|
| Name | BDBM50366034 |
|---|
| Synonyms: | CHEMBL186422 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C9H7NO |
|---|
| Mol. Mass. | 145.158 |
|---|
| SMILES | O=c1ccc2ccccc2[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
