| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 1 |
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| Ligand | BDBM23165 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_806027 (CHEMBL1960544) |
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| EC50 | 0.29±n/a nM |
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| Citation |  Nakamura, T; Asano, M; Sekiguchi, Y; Mizuno, Y; Tamaki, K; Nara, F; Kawase, Y; Yabe, Y; Nakai, D; Kamiyama, E; Urasaki-Kaneno, Y; Shimozato, T; Doi-Komuro, H; Kagari, T; Tomisato, W; Inoue, R; Nagasaki, M; Yuita, H; Oguchi-Oshima, K; Kaneko, R; Nishi, T Synthesis and evaluation of CS-2100, a potent, orally active and S1P(3)- sparing S1P(1) agonist. Eur J Med Chem51:92-8 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 1 |
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| Name: | Sphingosine 1-phosphate receptor 1 |
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| Synonyms: | CD_antigen=CD363 | Edg1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor 1 | S1P receptor Edg-1 | S1P1 | S1PR1_RAT | S1pr1 | Sphingosine 1-phosphate receptor Edg-1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42770.88 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1463793 |
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| Residue: | 383 |
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| Sequence: | MVSSTSIPVVKALRSQVSDYGNYDIIVRHYNYTGKLNIGVEKDHGIKLTSVVFILICCLI
ILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFL
REGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNSSRSFLLISACWVISLILGGLPI
MGWNCISSLSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRK
NISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKAKTCDILYKAEYFLVL
AVLNSGTNPIIYTLTNKEMRRAFIRIISCCKCPNGDSAGKFKRPIIPGMEFSRSKSDNSS
HPQKDDGDNPETIMSSGNVNSSS
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| BDBM23165 |
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| n/a |
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| Name | BDBM23165 |
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| Synonyms: | CHEMBL366208 | FTY720-phosphate, (S)-2 | [(2S)-2-amino-3-hydroxy-2-[2-(4-octylphenyl)ethyl]propoxy]phosphonic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C19H34NO5P |
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| Mol. Mass. | 387.4507 |
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| SMILES | CCCCCCCCc1ccc(CC[C@](N)(CO)COP(O)(O)=O)cc1 |r| |
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| Structure | 
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