Ki Summary

Reaction Details

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Target

Neurotensin receptor type 1

Ligand

BDBM50366296

Substrate/Competitor

n/a

Meas. Tech.

ChEBML_144304

180±n/a nM

Citation

Cain, GA; Christos, TE; Johnson, AL; Pottorf, RS; Confalone, PN; William Tam, S; Schmidt, WK Neurotensin receptor binding and antinociceptive activity for lipophilic N-amido neurotensin(913) analogs Bioorg Med Chem Lett3:2055-2060 (1993) Article

More Info.:

Get all data from this article, Assay Method

Neurotensin receptor type 1

Name:

Neurotensin receptor type 1

Synonyms:

NTR1_RAT | Neurotensin receptor 1 | Ntsr | Ntsr1

Type:

PROTEIN

Mol. Mass.:

47070.64

Organism:

Rattus norvegicus

Description:

ChEMBL_1466612

Residue:

424

Sequence:

MHLNSSVPQGTPGEPDAQPFSGPQSEMEATFLALSLSNGSGNTSESDTAGPNSDLDVNTD
IYSKVLVTAIYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLA
MPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTL
MSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSGDGTHPGGLVCTPIVDTATVKVVIQV
NTFMSFLFPMLVISILNTVIANKLTVMVHQAAEQGRVCTVGTHNGLEHSTFNMTIEPGRV
QALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYV
SSAINPILYNLVSANFRQVFLSTLACLCPGWRHRRKKRPTFSRKPNSMSSNHAFSTSATR
ETLY

BDBM50366296

n/a

Name

BDBM50366296

Synonyms:

CHEMBL1790463

Type

Small organic molecule

Emp. Form.

C42H64N6O8

Mol. Mass.

780.993

SMILES

CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN)NC(=O)C12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](CC(C)C)C(O)=O |TLB:42:41:44:36.37.38,42:37:44:43.41.40,38:39:43:36.37.42,THB:38:37:43:44.39.40|

Structure