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TargetGag-Pol polyprotein [489-587]
LigandBDBM50281639
Substrate/Competitorn/a
Meas. Tech.ChEBML_157566
Ki 47±n/a nM
Citation Sawyer, TFisher, JHester, JSmith, CTomasselli, ATarpley, WBurton, PHui, JMcQuade, TConradi, RBradford, VLiu, LKinner, JTustin, JAlexander, DHarrison, AEmmert, DStaples, DMaggiora, LZhang, YPoorman, RDunna, BRao, CScarborough, PLowther, WCraik, CDeCamp, DMoon, JHowe, WHeinrikson, R Peptidomimetic inhibitors of human immunodeficiency virus protease (HIV-PR): Design, enzyme binding and selectivity, antiviral efficacy, and cell permeability properties Bioorg Med Chem Lett3:819-824 (1993)    Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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  Blast E-value cutoff:
BDBM50281639
n/a
NameBDBM50281639
Synonyms:(2S,4S,5S)-6-Cyclohexyl-5-hexanoylamino-4-hydroxy-2-isopropyl-hexanoic acid {(S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide | CHEMBL168779
TypeSmall organic molecule
Emp. Form.C33H56N4O4
Mol. Mass.572.8221
SMILESCCCCCC(=O)N[C@@H](CC1CCCCC1)[C@@H](O)C[C@@H](C(C)C)C(=O)N[C@@H](C(C)CC)C(=O)NCc1ccccn1
Structure
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