| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50282036 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_155135 (CHEMBL764097) |
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| IC50 | 15±n/a nM |
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| Citation |  Wood, L; Whittaker, M; Timmis, DJ; Thompson, TM; Saroglou, L; Miller, A; Davidson, AH; Christodoulou, MS; Cackett, KS; Bowles, SA; Bebbington, DS Cyclic ether acetal platelet activating factor (PAF) receptor antagonists II: imidazo[4,5-c]pyridyl derivatives Bioorg Med Chem Lett3:1499-1504 (1993) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39219.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | PAF Platelet activating factor PTAFR HUMAN::P25105 |
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| Residue: | 342 |
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| Sequence: | MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
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| BDBM50282036 |
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| n/a |
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| Name | BDBM50282036 |
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| Synonyms: | 1-{3-[(2S,5R)-5-(3,4-Dimethoxy-phenyl)-tetrahydro-furan-2-yloxy]-propyl}-2-methyl-1H-imidazo[4,5-c]pyridine | CHEMBL288329 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27N3O4 |
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| Mol. Mass. | 397.4675 |
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| SMILES | COc1ccc(cc1OC)[C@H]1CC[C@@H](OCCCn2c(C)nc3cnccc23)O1 |
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| Structure | 
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