| Reaction Details |
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 | Report a problem with these data |
| Target | 3-phosphoshikimate 1-carboxyvinyltransferase |
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| Ligand | BDBM50283582 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_64952 (CHEMBL857525) |
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| Ki | 2500±n/a nM |
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| Citation |  Miller, MJ; Braccolino, DS; Clearly, DG; Ream, JE; Walker, MC; Sikorski, JA EPSP synthase inhibitor design IV. New aromatic substrate analogs and symmetrical inhibitors containing novel 3-phosphate mimics. Bioorg Med Chem Lett4:2605-2608 (1994) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-phosphoshikimate 1-carboxyvinyltransferase |
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| Name: | 3-phosphoshikimate 1-carboxyvinyltransferase |
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| Synonyms: | 5-enolpyruvylshikimate-3-phosphate synthase | AROA_ECOLI | aroA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46089.22 |
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| Organism: | Escherichia coli (strain K12) |
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| Description: | ChEMBL_65087 |
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| Residue: | 427 |
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| Sequence: | MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTAL
GVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPR
MKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTA
PLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVE
GDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGE
LNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVE
EGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQL
ARISQAA
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| BDBM50283582 |
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| n/a |
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| Name | BDBM50283582 |
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| Synonyms: | 2-(3-Carboxy-5-dicarboxymethoxy-phenoxy)-malonic acid | CHEMBL329115 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H10O12 |
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| Mol. Mass. | 358.2113 |
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| SMILES | OC(=O)C(Oc1cc(OC(C(O)=O)C(O)=O)cc(c1)C(O)=O)C(O)=O |
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| Structure | 
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