| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM50021959 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_40415 |
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| IC50 | >20000±n/a nM |
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| Citation |  Buynak, JD; Geng, B; Bachmann, B; Ling, Hua The synthesis and lactamase inhibitory activity of 6-(carboxymethylene)penicillins and 7-(carboxymethylene)cephalosporins Bioorg Med Chem Lett5:1513-1518 (1995) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | AMPC_ENTCL | ampC |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41306.67 |
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| Organism: | Enterobacter cloacae |
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| Description: | ChEMBL_40258 |
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| Residue: | 381 |
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| Sequence: | MMRKSLCCALLLGISCSALATPVSEKQLAEVVANTITPLMKAQSVPGMAVAVIYQGKPHY
YTFGKADIAANKPVTPQTLFELGSISKTFTGVLGGDAIARGEISLDDAVTRYWPQLTGKQ
WQGIRMLDLATYTAGGLPLQVPDEVTDNASLLRFYQNWQPQWKPGTTRLYANASIGLFGA
LAVKPSGMPYEQAMTTRVLKPLKLDHTWINVPKAEEAHYAWGYRDGKAVRVSPGMLDAQA
YGVKTNVQDMANWVMANMAPENVADASLKQGIALAQSRYWRIGSMYQGLGWEMLNWPVEA
NTVVEGSDSKVALAPLPVAEVNPPAPPVKASWVHKTGSTGGFGSYVAFIPEKQIGIVMLA
NTSYPNPARVEAAYHILEALQ
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| BDBM50021959 |
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| n/a |
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| Name | BDBM50021959 |
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| Synonyms: | CHEMBL777 | MM 14151 | US9120808, Clavulanic acid potassium salt | antibiotic MM 14151 | clavulanic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C8H9NO5 |
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| Mol. Mass. | 199.1608 |
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| SMILES | OC\C=C1/O[C@@H]2CC(=O)N2[C@H]1C(O)=O |r| |
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| Structure | 
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