| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein kinase C gamma type |
|---|
| Ligand | BDBM3152 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_161274 |
|---|
| IC50 | 13±n/a nM |
|---|
| Citation |  Lai, Y; Mendoza, J; Hubbard, F; Kalter, K Synthesis and PKC inhibitory activities of balanol analogs with a cyclopentane substructure Bioorg Med Chem Lett5:2155-2160 (1995) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protein kinase C gamma type |
|---|
| Name: | Protein kinase C gamma type |
|---|
| Synonyms: | KPCG_HUMAN | PKC gamma | PKC-gamma | PKCG | PRKCG | Protein kinase C gamma | Protein kinase C gamma type | Protein kinase C, PKC; classical/novel | Protein kinase C, gamma |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 78458.05 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | The recombinant human PKC enzymes were
produced using a baculovirus expression system in SF9 cells
|
|---|
| Residue: | 697 |
|---|
| Sequence: | MAGLGPGVGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG
KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSL
LYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTADEIHVTVGEA
RNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRL
SVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQ
KFEACNYPLELYERVRMGPSSSPIPSPSPSPTDPKRCFFGASPGRLHISDFSFLMVLGKG
SFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQL
HSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRD
LKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWS
FGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGS
GPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCGRSGENFDKFFTRAAPALTPPDRL
VLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVM
|
|
|
|---|
| BDBM3152 |
|---|
| n/a |
|---|
| Name | BDBM3152 |
|---|
| Synonyms: | 2-{[2,6-dihydroxy-4-({[(3R,4R)-4-[(4-hydroxybenzene)amido]pyrrolidin-3-yl]oxy}carbonyl)phenyl]carbonyl}-3-hydroxybenzoic acid | Balanol analog 4 | CHEMBL59828 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H22N2O10 |
|---|
| Mol. Mass. | 522.4603 |
|---|
| SMILES | OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1CNC[C@H]1NC(=O)c1ccc(O)cc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
