| Reaction Details |
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 | Report a problem with these data |
| Target | 2-5A-dependent ribonuclease |
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| Ligand | BDBM50366437 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_164142 (CHEMBL771466) |
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| IC50 | 50±n/a nM |
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| Citation |  Sawai, H; Ito, T; Kokaji, K; Shimazu, M; Shinozuka, K; Taira, H Synthesis and properties of 25 and 35 linked -oligoriboadenylates Bioorg Med Chem Lett6:1785-1790 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 2-5A-dependent ribonuclease |
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| Name: | 2-5A-dependent ribonuclease |
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| Synonyms: | 2-5A-dependent RNase | 2-5A-dependent ribonuclease | RN5A_MOUSE | RNase L | Ribonuclease 4 | Ribonuclease L | Rnasel | Rns4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 83274.00 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_195099 |
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| Residue: | 735 |
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| Sequence: | METPDYNTPQGGTPSAGSQRTVVEDDSSLIKAVQKGDVVRVQQLLEKGADANACEDTWGW
TPLHNAVQAGRVDIVNLLLSHGADPHRRKKNGATPFIIAGIQGDVKLLEILLSCGADVNE
CDENGFTAFMEAAERGNAEALRFLFAKGANVNLRRQTTKDKRRLKQGGATALMSAAEKGH
LEVLRILLNDMKAEVDARDNMGRNALIRTLLNWDCENVEEITSILIQHGADVNVRGERGK
TPLIAAVERKHTGLVQMLLSREGINIDARDNEGKTALLIAVDKQLKEIVQLLLEKGADKC
DDLVWIARRNHDYHLVKLLLPYVANPDTDPPAGDWSPHSSRWGTALKSLHSMTRPMIGKL
KIFIHDDYKIAGTSEGAVYLGIYDNREVAVKVFRENSPRGCKEVSCLRDCGDHSNLVAFY
GREDDKGCLYVCVSLCEWTLEEFLRLPREEPVENGEDKFAHSILLSIFEGVQKLHLHGYS
HQDLQPQNILIDSKKAVRLADFDQSIRWMGESQMVRRDLEDLGRLVLYVVMKGEIPFETL
KTQNDEVLLTMSPDEETKDLIHCLFSPGENVKNCLVDLLGHPFFWTWENRYRTLRNVGNE
SDIKVRKCKSDLLRLLQHQTLEPPRSFDQWTSKIDKNVMDEMNHFYEKRKKNPYQDTVGD
LLKFIRNIGEHINEEKKRGMKEILGDPSRYFQETFPDLVIYIYKKLKETEYRKHFPQPPP
RLSVPEAVGPGGIQS
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| BDBM50366437 |
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| n/a |
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| Name | BDBM50366437 |
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| Synonyms: | CHEMBL608874 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H36N15O19P3 |
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| Mol. Mass. | 991.6065 |
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| SMILES | Nc1ncnc2n(cnc12)C1O[C@H](COP(O)(=O)O[C@@H]2[C@H](O)[C@@H](COP(O)(=O)O[C@@H]3[C@H](O)[C@@H](OP(O)(O)=O)O[C@H]3n3cnc4c(N)ncnc34)O[C@H]2n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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