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TargetGag-Pol polyprotein [489-587]
LigandBDBM50288192
Substrate/Competitorn/a
Meas. Tech.ChEBML_157564
Ki 0.600000±n/a nM
Citation Abbenante, GBergman, DBrinkworth, RMarch, DReid, RHunt, PJames, IDancer, RGarnham, BStoermer, MFairlie, D Structure-activity relationships for macrocyclic peptidomimetic inhibitors of HIV-1 protease Bioorg Med Chem Lett6:2531-2536 (1996)    Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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  Blast E-value cutoff:
BDBM50288192
n/a
NameBDBM50288192
Synonyms:CHEMBL83186 | N-[2-Hydroxy-2-((S)-8-isopropyl-6,9-dioxo-2-oxa-7,10-diaza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-trien-11-yl)-ethyl]-N-(3-methyl-butyl)-benzenesulfonamide
TypeSmall organic molecule
Emp. Form.C29H40N4O7S
Mol. Mass.588.716
SMILESCC(C)CCN(C[C@@H](O)[C@H]1Cc2ccc(OCCCC(=O)N[C@@H](CC(N)=O)C(=O)N1)cc2)S(=O)(=O)c1ccccc1
Structure
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