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TargetGastrin-releasing peptide receptor
LigandBDBM50288242
Substrate/Competitorn/a
Meas. Tech.ChEBML_71531
Ki>10000±n/a nM
Citation Eden, JHall, MHigginbottom, MHorwell, DHowson, WHughes, JJordan, RLewthwaite, RMartin, KMcKnight, APinnock, RPritchard, MSuman-Chauhan, NWilliams, S PD 165929 the first high affinity non-peptide neuromedin-B (NMB) receptor selective antagonist Bioorg Med Chem Lett6:2617-2622 (1996)    Article
More Info.:Get all data from this article,  Assay Method
 
Gastrin-releasing peptide receptor
Name:Gastrin-releasing peptide receptor
Synonyms:Bombesin 2 | GRP-R | GRP-preferring bombesin receptor | GRPR | GRPR_HUMAN | Gastrin releasing peptide receptor | Gastrin-releasing peptide receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:43214.53
Organism:Homo sapiens (Human)
Description:Bombesin 2 GRPR 0::P30550
Residue:384
Sequence:
MALNDCFLLNLEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNIT
LIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQ
LTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSD
LHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQS
AYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLH
FVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTCMTS
LKSTNPSVATFSLINGNICHERYV
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  Blast E-value cutoff:
BDBM50288242
n/a
NameBDBM50288242
Synonyms:2-[3-(2,6-Diisopropyl-phenyl)-ureido]-3-(1H-indol-3-yl)-2-methyl-N-phenethyl-propionamide | CHEMBL313829
TypeSmall organic molecule
Emp. Form.C33H40N4O2
Mol. Mass.524.6963
SMILESCC(C)c1cccc(C(C)C)c1NC(=O)NC(C)(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1
Structure
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