| Reaction Details |
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 | Report a problem with these data |
| Target | Gastrin-releasing peptide receptor |
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| Ligand | BDBM50288252 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_71531 |
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| Ki | 0.700000±n/a nM |
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| Citation |  Eden, J; Hall, M; Higginbottom, M; Horwell, D; Howson, W; Hughes, J; Jordan, R; Lewthwaite, R; Martin, K; McKnight, A; Pinnock, R; Pritchard, M; Suman-Chauhan, N; Williams, S PD 165929 the first high affinity non-peptide neuromedin-B (NMB) receptor selective antagonist Bioorg Med Chem Lett6:2617-2622 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gastrin-releasing peptide receptor |
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| Name: | Gastrin-releasing peptide receptor |
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| Synonyms: | Bombesin 2 | GRP-R | GRP-preferring bombesin receptor | GRPR | GRPR_HUMAN | Gastrin releasing peptide receptor | Gastrin-releasing peptide receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43214.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Bombesin 2 GRPR 0::P30550 |
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| Residue: | 384 |
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| Sequence: | MALNDCFLLNLEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNIT
LIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQ
LTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSD
LHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQS
AYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLH
FVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTCMTS
LKSTNPSVATFSLINGNICHERYV
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| BDBM50288252 |
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| n/a |
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| Name | BDBM50288252 |
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| Synonyms: | Bombesin analogue | CHEMBL269432 |
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| Type | Small organic molecule |
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| Emp. Form. | C51H72N10O12 |
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| Mol. Mass. | 1017.1772 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(O)=O |
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| Structure | 
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