| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
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| Ligand | BDBM50288585 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_3344 (CHEMBL619044) |
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| Ki | 4.5±n/a nM |
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| Citation |  Fancelli, D; Caccia, C; Fornaretto, M; McArthur, R; Severino, D; Vaghi, F; Varasi, M Serotoninergic 5-HT3 and 5-HT4 receptor activities of dihydrobenzofuran carboxylic acid derivatives Bioorg Med Chem Lett6:263-266 (1996) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 4 |
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| Name: | 5-hydroxytryptamine receptor 4 |
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| Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4L | 5-HT4S | 5-hydroxytryptamine receptor 4 | 5HT4R_RAT | Htr4 | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46117.31 |
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| Organism: | RAT |
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| Description: | 5-HT4 HTR4 RAT::Q62758 |
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| Residue: | 406 |
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| Sequence: | MDRLDANVSSNEGFGSVEKVVLLTFFAMVILMAILGNLLVMVAVCRDRQLRKIKTNYFIV
SLAFADLLVSVLVNAFGAIELVQDIWFYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDVIEKRKFNHNSN
STFCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRP
QTADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEKVWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRD
TVECGGQWESRCHLTATSPLVAAQPVIRRPQDNDLEDSCSLKRSQS
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| BDBM50288585 |
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| n/a |
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| Name | BDBM50288585 |
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| Synonyms: | 4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid 3-piperidin-1-yl-propyl ester | CHEMBL91842 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H23ClN2O3 |
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| Mol. Mass. | 338.829 |
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| SMILES | Nc1c2CCOc2c(cc1Cl)C(=O)OCCCN1CCCCC1 |
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| Structure | 
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