Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 4 | ||
Ligand | BDBM50288584 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_3344 | ||
Ki | 1.9±n/a nM | ||
Citation | Fancelli, D; Caccia, C; Fornaretto, M; McArthur, R; Severino, D; Vaghi, F; Varasi, M Serotoninergic 5-HT3 and 5-HT4 receptor activities of dihydrobenzofuran carboxylic acid derivatives Bioorg Med Chem Lett6:263-266 (1996) Article | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 4 | |||
Name: | 5-hydroxytryptamine receptor 4 | ||
Synonyms: | 5-HT-4 | 5-HT4 | 5-HT4L | 5-HT4S | 5-hydroxytryptamine receptor 4 | 5HT4R_RAT | Htr4 | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 46117.31 | ||
Organism: | RAT | ||
Description: | 5-HT4 HTR4 RAT::Q62758 | ||
Residue: | 406 | ||
Sequence: |
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BDBM50288584 | |||
n/a | |||
Name | BDBM50288584 | ||
Synonyms: | (S)-3-[(4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carbonyl)-amino]-1-butyl-1-azonia-bicyclo[2.2.2]octane; bromide | CHEMBL423504 | ||
Type | Small organic molecule | ||
Emp. Form. | C20H29ClN3O2 | ||
Mol. Mass. | 378.916 | ||
SMILES | CCCC[N+]12CCC(CC1)[C@@H](C2)NC(=O)c1cc(Cl)c(N)c2CCOc12 |wU:10.13,(15.06,.2,;13.73,.93,;12.42,.18,;11.12,.89,;9.81,.14,;8.52,.95,;7.13,.23,;7.06,-1.31,;7.89,-.15,;8.53,-.78,;8.38,-2.13,;9.74,-1.4,;8.32,-3.67,;6.96,-4.4,;5.64,-3.58,;6.9,-5.94,;5.53,-6.65,;5.46,-8.21,;4.13,-8.96,;6.76,-9.01,;6.72,-10.57,;8.13,-8.3,;9.58,-8.84,;10.54,-7.63,;9.67,-6.34,;8.18,-6.76,)| | ||
Structure |