| Reaction Details |
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 | Report a problem with these data |
| Target | Neuromedin-B receptor |
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| Ligand | BDBM50289794 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_88176 |
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| Ki | 37±n/a nM |
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| Citation |  Horwell, D; Kneen, C; Pritchard, M; Ratcliffe, G; Roberts, E; Suman-Chauhan, N; Steiner, K; Betche, H Design and synthesis of a targeted set of aromatic amino acid derivatives for identification of new lead compounds Bioorg Med Chem Lett7:1957-1962 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuromedin-B receptor |
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| Name: | Neuromedin-B receptor |
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| Synonyms: | Bombesin 1 | NMB-R | NMBR | NMBR_HUMAN | Neuromedin B | Neuromedin B receptor | Neuromedin-B receptor | Neuromedin-B-preferring bombesin receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43447.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Bombesin 1 NMBR 0::P28336 |
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| Residue: | 390 |
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| Sequence: | MPSKSLSNLSVTTGANESGSVPEGWERDFLPASDGTTTELVIRCVIPSLYLLIITVGLLG
NIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWMFGKVGCKLIP
VIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGIWVVSVLLAVPEAV
FSEVARISSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHIAKTLI
KSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEIDPSL
GHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSSSAV
RMTSLKSNAKNMVTNSVLLNGHSMKQEMAL
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| BDBM50289794 |
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| n/a |
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| Name | BDBM50289794 |
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| Synonyms: | CHEMBL292119 | [2-(1H-Indol-3-yl)-1-isobutylcarbamoyl-ethyl]-carbamic acid 1-trityl-1H-imidazol-4-ylmethyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C39H39N5O3 |
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| Mol. Mass. | 625.7587 |
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| SMILES | CC(C)CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OCc1cn(cn1)C(c1ccccc1)(c1ccccc1)c1ccccc1 |
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| Structure | 
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