| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinoic acid receptor beta |
|---|
| Ligand | BDBM50048280 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_195497 |
|---|
| Ki | 34±n/a nM |
|---|
| Citation |  Diaz, P; Michel, S; Stella, L; Charpentier, B Synthesis and biological activities of new heterocyclic aromatic retinoids Bioorg Med Chem Lett7:2289-2294 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinoic acid receptor beta |
|---|
| Name: | Retinoic acid receptor beta |
|---|
| Synonyms: | HAP | HBV-activated protein | NR1B2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RAR-epsilon | RARB | RARB_HUMAN | Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta | Retinoic acid receptor beta | Retinoid receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 50498.70 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1458015 |
|---|
| Residue: | 455 |
|---|
| Sequence: | MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPSPAT
IETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
IYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEM
TAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIV
EFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
GFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALK
IYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGH
EPLTPSSSGNTAEHSPSISPSSVENSGVSQSPLVQ
|
|
|
|---|
| BDBM50048280 |
|---|
| n/a |
|---|
| Name | BDBM50048280 |
|---|
| Synonyms: | 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid | 6-(3-adamantan-1-yl-4-methoxyphenyl)naphthalene-2-carboxylic acid | ADAPALENE | CHEMBL1265 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H28O3 |
|---|
| Mol. Mass. | 412.5201 |
|---|
| SMILES | COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O |TLB:7:8:11:15.14.13,THB:9:10:13:17.8.16,9:8:11.10.15:13,16:8:11:15.14.13,16:14:11:17.9.8| |
|---|
| Structure | 
|
|---|
Search and Browse
