Ki Summary

Reaction Details

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Target

D(3) dopamine receptor

Ligand

BDBM50290223

Substrate/Competitor

n/a

Meas. Tech.

ChEBML_58772

4.5±n/a nM

Citation

Belliotti, TR; Kesten, SR; Rubin, JR; Wustrow, DJ; Georgic, LM; Zoski, KT; Akunne, HC; Wise, LD Novel cyclohexyl amides as potent and selective D3 dopamine receptor ligands Bioorg Med Chem Lett7:2403-2408 (1997) Article

More Info.:

Get all data from this article, Assay Method

D(3) dopamine receptor

Name:

D(3) dopamine receptor

Synonyms:

Type:

n/a

Mol. Mass.:

44243.43

Organism:

Homo sapiens (Human)

Description:

n/a

Residue:

400

Sequence:

MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC

BDBM50290223

n/a

Name

BDBM50290223

Synonyms:

CHEMBL309979 | Cyclohexanecarboxylic acid (4-{2-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-amide

Type

Small organic molecule

Emp. Form.

C25H37Cl2N3O

Mol. Mass.

466.487

SMILES

Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)C3CCCCC3)CC2)c1Cl |wU:12.11,wD:15.18,(20.33,-3.82,;19.58,-5.18,;20.4,-6.5,;19.65,-7.84,;18.11,-7.88,;17.31,-6.55,;15.77,-6.59,;15.03,-7.93,;13.49,-7.96,;12.68,-6.65,;11.14,-6.69,;10.38,-8.03,;8.84,-8.03,;8.05,-9.36,;6.51,-9.38,;5.75,-8.04,;6.51,-6.71,;8.05,-6.69,;4.21,-8.05,;3.44,-9.38,;1.89,-9.38,;4.21,-10.72,;5.74,-10.71,;6.5,-12.04,;5.73,-13.36,;4.19,-13.36,;3.44,-12.04,;13.43,-5.31,;14.97,-5.27,;18.05,-5.21,;17.24,-3.89,)|

Structure