| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
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| Ligand | BDBM50098668 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_38792 |
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| EC50 | 2000±n/a nM |
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| Citation |  Beeley L; Berge J; Chapman H; Dean D; Kelly J; Lowden K; Kotecha N; Morgan H; Rami H; Thompson M; Vong A; Ward R A simplified template approach towards the synthesis of a potent beta-3 adrenoceptor agonist at the human receptor Bioorg Med Chem Lett 7:219-224 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-3 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor and beta-3 adrenergic receptor |
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| Synonyms: | ADRB3 | B3AR | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 43534.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 408 |
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| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
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| BDBM50098668 |
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| n/a |
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| Name | BDBM50098668 |
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| Synonyms: | 4-(3-tert-Butylamino-2-hydroxy-propoxy)-1,3-dihydro-benzoimidazol-2-one | CGP-12177A | CHEMBL36060 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H21N3O3 |
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| Mol. Mass. | 279.3348 |
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| SMILES | CC(C)(C)NC[C@H](O)COc1cccc2[nH]c(=O)[nH]c12 |
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| Structure | 
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