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TargetBeta-3 adrenergic receptor
LigandBDBM50098668
Substrate/Competitorn/a
Meas. Tech.ChEBML_38792
EC50 2000±n/a nM
Citation Beeley LBerge JChapman HDean DKelly JLowden KKotecha NMorgan HRami HThompson MVong AWard R A simplified template approach towards the synthesis of a potent beta-3 adrenoceptor agonist at the human receptor Bioorg Med Chem Lett 7:219-224 (1997)    Article
More Info.:Get all data from this article,  Assay Method
 
Beta-3 adrenergic receptor
Name:Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Synonyms:ADRB3 | B3AR | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:43534.88
Organism:Homo sapiens (Human)
Description:n/a
Residue:408
Sequence:
MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
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  Blast E-value cutoff:
BDBM50098668
n/a
NameBDBM50098668
Synonyms:4-(3-tert-Butylamino-2-hydroxy-propoxy)-1,3-dihydro-benzoimidazol-2-one | CGP-12177A | CHEMBL36060
TypeSmall organic molecule
Emp. Form.C14H21N3O3
Mol. Mass.279.3348
SMILESCC(C)(C)NC[C@H](O)COc1cccc2[nH]c(=O)[nH]c12
Structure
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