| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-3 adrenergic receptor |
|---|
| Ligand | BDBM50098668 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_38792 |
|---|
| EC50 | 2000±n/a nM |
|---|
| Citation |  Beeley, L; Berge, J; Chapman, H; Dean, D; Kelly, J; Lowden, K; Kotecha, N; Morgan, H; Rami, H; Thompson, M; Vong, A; Ward, R A simplified template approach towards the synthesis of a potent beta-3 adrenoceptor agonist at the human receptor Bioorg Med Chem Lett7:219-224 (1997) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-3 adrenergic receptor |
|---|
| Name: | Beta-3 adrenergic receptor |
|---|
| Synonyms: | ADRB3 | ADRB3R | ADRB3_HUMAN | B3AR | Beta-2 adrenergic receptor and beta-3 adrenergic receptor | Beta-3 adrenoceptor | Beta-3 adrenoreceptor | adrenergic Beta3 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 43534.88 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 408 |
|---|
| Sequence: | MAPWPHENSSLAPWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIV
AIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALTGHWPLGATGCELWTSVDVLC
VTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRV
GADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRG
ELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPARLLPLREHRALCTLGLIMGT
FTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRSAFRRLL
CRCGRRLPPEPCAAARPALFPSGVPAARSSPAQPRLCQRLDGASWGVS
|
|
|
|---|
| BDBM50098668 |
|---|
| n/a |
|---|
| Name | BDBM50098668 |
|---|
| Synonyms: | 4-(3-tert-Butylamino-2-hydroxy-propoxy)-1,3-dihydro-benzoimidazol-2-one | CGP-12177A | CHEMBL36060 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H21N3O3 |
|---|
| Mol. Mass. | 279.3348 |
|---|
| SMILES | CC(C)(C)NC[C@H](O)COc1cccc2[nH]c(=O)[nH]c12 |
|---|
| Structure | 
|
|---|
Search and Browse
