| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50290872 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_138866 |
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| Ki | 60±n/a nM |
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| Citation |  Dondio, G; Ronzoni, S; Petrillo, P; DesJarlais, RL; Raveglia, LF Pyrrolooctahydroisoquinolines as potent and selective opioid receptor ligands: SAR analysis and docking studies Bioorg Med Chem Lett7:2967-2972 (1997) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44431.62 |
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| Organism: | MOUSE |
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| Description: | OPIATE Mu OPRM1 MOUSE::P42866 |
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| Residue: | 398 |
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| Sequence: | MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50290872 |
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| n/a |
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| Name | BDBM50290872 |
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| Synonyms: | (-)-rel-3-((4aR,12aS)-2-methyl-1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridin-4a-yl)phenol | 3-((4aS,12aR)-2-Methyl-1,3,4,5,12,12a-hexahydro-2H-2,6-diaza-naphthacen-4a-yl)-phenol | CHEMBL327745 | SB-213698 | TAN-67 | Tan-67 (racemic) |
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| Type | Small organic molecule |
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| Emp. Form. | C23H24N2O |
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| Mol. Mass. | 344.4495 |
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| SMILES | CN1CC[C@@]2(Cc3nc4ccccc4cc3C[C@H]2C1)c1cccc(O)c1 |r| |
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| Structure | 
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